The following issues listed be had been to be caused when IPv6 is disabled on the server. Please share your experience with disabling IPv6.
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LDAP test over UDP may not work against domain controllers that are running Windows Server 2008. See Microsoft article
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Some applications might not work like Remote Assistance, HomeGroup, DirectAccess, and Windows Mail.
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On Windows Small Business Server 2008, the following issues might appear after reboot:
- Exchange 2010 Unified Messaging Server does not support IPv6, so to avoid any unwanted issues while installing Exchange 2010, disable IPv6 by applying the registry key which I have posted here.